1. HOW CAN I RECOGNIZE A MELANOMA EARLY ON?
Pay special attention to any change in pre-existing moles; use the ABCDE rule, EGF and Ugly Duckling Sign.
2. WHAT DOES HAVING A BIOPSY OF A MOLE AT RISK REALLY MEAN?
This examination will show whether the lesion is benign and malignant.
3. WHAT CAUSES MELANOMA?
4. DOES BEING IN THE SUN INCREASE THE LIKELIHOOD OF GETTING MELANOMA?
5. WHAT ARE THE BEST TREATMENTS AVAILABLE TODAY?
If there is metastasis, treatment will be mainly immunotherapy based on anti PD-1 antibodies, possibly in combination with anti CTLA-4 antibodies, along with so-called BRAF and MEK inhibitor therapy for people whose melanoma has the V600 mutation of the BRAF gene.
Treatment choices are made on the basis of the particular characteristics of the patient and the disease. The multidisciplinary treatment team of professionals will design a personal treatment program appropriate for each patient.
6. ARE THERE VACCINES AGAINST MELANOMA?
7. WHAT IS CELLULAR TREATMENT OF MELANOMA?
TIL-based therapies to treat melanoma go back a long way. They have recently come back into the limelight on account of the latest very promising data from some European and US studies. Indeed, the procedure to obtain FDA approval has been started for Lifileucel, a TIL-based therapy. The situation is different for Car-Ts (Chimeric Antigen Receptor T-cell therapies). Although the use of Car-Ts in clinical practice has changed in some cases of cancer of the blood, when it comes to solid tumors, like melanoma, research is still at the early trial level.
8. DO HORMONES AFFECT WHETHER YOU GET MELANOMA?
In conclusion, it is generally not considered necessary to modify or discontinue hormone therapies if a person is diagnosed with melanoma. However, a gynecologist should be consulted to assess the individual risk-benefit of hormone treatment.
9. IS PREGNANCY A PROBLEM?
10. IS THERE A SPECIAL DIET FOR MELANOMA?
11. WHY SHOULD PEOPLE GO TO THEIR GP OR FAMILY PAEDIATRICIAN FOR A CHECK-UP?
12. WHY IS MULTIMEDIA TRAINING OF DOCTORS IMPORTANT?